While this blockage could enable patients to take lower doses of prescription drugs, it could also cause a toxic buildup of pharmaceutical chemicals in the body. Most CBD oil side effects, such as drowsiness and fatigue, are similar to hemp oil side effects, even though this hemp fiber-derived product usually doesn’t contain any CBD or THC. With its low potential for addiction and abuse, CBD’s withdrawal effects should be minimal. But each person must weigh the potential risk versus benefits for themselves.

As an increasing number of states legalize medicinal and/or recreational use of marijuana, the market for cannabis products has exploded. One of these products, cannabidiol (CBD) oil, has gained recent popularity for its purported ability to reduce pain, insomnia and anxiety without producing any “highs” like its psychoactive cousin tetrahydrocannabinol (THC). In 2013, a CNN program that featured Charlotte’s Web cannabis brought increased attention to the use of CBD in the treatment of seizure disorders. Since then, 16 states have passed laws to allow the use of CBD products with a physician’s recommendation (instead of a prescription) for treatment of certain medical conditions.

The primary endpoints included both clinical disease activity indices and endoscopic disease activity. Both disease activity and the endoscopic disease severity decreased significantly in the THC-treated group compared with the placebo-treated group after eight weeks of therapy. However, it is worth noting the baseline CRP and fecal calprotectin levels were numerically higher in the placebo-treated groups than in the treatment group. Furthermore, the quality of the study cannot be fully ascertained where to buy hemp oil until published in full.

This quality makes CBD an appealing option for those who are looking for relief from pain and other symptoms without the mind-altering effects of marijuana or certain pharmaceutical drugs. By slowing down how the body metabolizes these drugs, CBD preserves the medication’s durability and prolongs its presence in the body. Effectively, CBD can increase and prolong the effects of drugs that increase the risk of bleeding and the usage of both simultaneously should be closely monitored by a medical professional. Their published article cites three specific studies to support the case for elevated enzymes.

Liver toxicity can happen when an individual has an adverse reaction to different substances, and drugs, alcohol, and even natural supplements can impact the normal liver function even in healthy people. This study, however, is the first one that suggests that CBD Oil can be just as bad for the liver, like all other chemicals. The study also found that there is also a possibility for herbal and drug interactions.

If you’re one of the millions of people who has been relying on CBD for your health for years, this is no doubt confusing and terrifying. The only product approved by the FDA for its medical value is Epidiolex. So, while it may be legal to use CBD in a state like Colorado or Alaska, if an employer follows federal regulations, the standardization and quality of a CBD product matters. Because if there’s even a small percentage of THC in that product, then a drug test might come back positive. And in lab studies, CBD has been shown to inhibit certain enzymes responsible for the metabolism of drugs, such as CYP2D6 and CYP3A4.